Active Drug Information

Tadalafil is the active drug present in Tadalista, which is categorized under the class of drugs called PDE5 (phosphodiesterase-5) antagonists. Sildenafil, Vardenafil, and Avanafil are other drugs that are categorized under the same class of drugs. Most physicians recommend this medicine who are looking for long-lasting effects, as it works for more than 35 hours. The FDA approved this ED drug in 2003.

Tadalafil looks after treating ED by boosting blood flow to the male organ during sexual arousal. Blood flow to the male organ should be enhanced to cause an erection on sexual excitement. Apart from erectile dysfunction, Tadalafil (Tadalista) is advised for the treatment of pulmonary arterial hypertension (PAH) and benign prostate hyperplasia (BPH). PAH symptoms include chest pain and breathlessness, while BPH symptoms include urinary troubles.

Mechanism of Action

Tadalista (Tadalafil) is an effective PDE5 inhibitor. PDE5 is an enzyme that the body naturally secretes. Upon oral intake, the drug nullifies the function of an enzyme called PDE5, preventing cyclic Guanosine Monophosphate (cGMP) degradation. When this action mechanism takes place, the body releases nitric oxide, a potent chemical that is secreted more during sexual arousal.

Nitric oxide then relaxes and opens up the arteries in the male organ, helping it to receive an adequate amount of blood for an erection during sexual stimulation. Tadalista does not cause a spontaneous erection soon after taking the medicine. The drug takes some time to absorb and work. It is essential for a man to undergo sexual stimulation 30 minutes after dosage to experience an erection.

Dosing Instructions

• Tadalista 5mg should be taken an hour before intending to indulge in sexual intercourse. Keep in mind that tadalafil will not work in the absence of sexual arousal.
• You should take a whole pill with water for appropriate drug absorption.
• If you take any other OTC or prescription medications, check with your doctor how and when to use them while using Tadalista.
• For the best effects, take the medicine on an empty stomach and avoid fatty foods. Fatty foods may delay the effectiveness or nullify the drug’s effects.
• You must avoid alcohol, illegal drugs, grapefruits, and high-fat meal before taking this generic ED medicine.
• Take Tadalista once a day or two, as it works for nearly 36 hours. Do not overdose with this weekend ED medication.
• Go through all the instructions and directions before using this generic Cialis medicine.

Storage and Disposal

• Tadalista tablets should be kept out of the reach of children and teenagers. Place the tablets in a very safe location.
• Store these ED pills in a cool, dry place, away from direct sunlight or moisture.
• Discard the outdated, unused, or medications that are no longer in use with proper care and caution.
• Talk to your pharmacist about how to carefully discard the pills that have crossed their expiry dates.

Precautions and Warnings

• Men allergic to any drug, including Tadalafil, should check with their doctor before using Tadalista tablets.
• Men with medical history of heart disease, diabetes, hypertension, hypercholesterolemia, kidney or liver disease, cancer, etc. should check with their doctor before treatment.
• Men taking prescription/OTC medications, multivitamins, natural or herbal supplements should check with their doctor before using this generic Cialis medication.
• Men should inform their doctor that they are using Tadalista for their ED problem if they are supposed to undergo any surgery.
• For some men who have a heart disease, sexual activity could put an extra pressure on the heart. If you take this ED drug and experience severe chest pain during sexual activity, seek medical attention.
• Tadalista is contraindicated to men who have been recommended to take medications containing alpha-blockers, nitrates, protease inhibitors, any other ED drugs.

Drug Interactions

• Nitroglycerine or nitrates – chest pain or angina medications
• Amlodipine or alpha-blockers – high blood pressure medications
• Protease inhibitors – HIV/AIDS medications
• Erythromycin or clarithromycin – antibiotics
• Itraconazole or ketoconazole – antifungals
• Avanafil, sildenafil, or vardenafil – other ED drugs

Contraindications

Those who have following medical problems are strictly prohibited from using Tadalista tablets:

• high blood pressure
• heart disease
• blood cancer, leukemia, sickle cell anemia
• retinopathy, severe eye conditions
• penile deformity (Peyronie’s disease)
• tadalafil allergy

Common Side Effects

• Nasal congestion
• Runny nose
• Back pain
• Hot flashes
• Headache

Seek medical attention immediately in case of chest pain, breathing troubles, dizziness, a painful or prolonged erection, hearing or vision loss, or fainting after taking the dosage or during sexual activity.